Researchers hope to test cancer fighting ? compound Cannabidiol
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SAN FRANCISCO (KGO) -- Medical marijuana and its psychoactive ingredient THC already provide relief, and often an accompanying buzz, for thousands of patients fighting cancer.
But more than five years ago, researchers at California Pacific Medical Center in San Francisco began focusing their attention on a far tamer compound in the marijuana plant, an ingredient called cannabidiol.
"Cannabidiol is a non-toxic agent from cannabis that is not psychoactive," says Sean McAllister, Ph.D., a lead researcher in the group's recent study.
McAllister and colleague Pierre Desprez, Ph.D., now believe they are ready for human trials, using the compound to treat metastatic cancer. The pair has produced a synthetic version of cannabidiol, also known as CBD, which they say targets a specific gene in the body related to the spread of cancer.
"We found this one compound, CBD, had a specific effect on metastatic cancer cells, very aggressive tumor cells. The bad cancer cells, the ones that spread throughout the body," said Desprez.
In their recently published study the team documented that effect on brain cancer in a large scale animal trial. They say brain scans revealed the disruption of the tumor cells after the cannabidiol was used to switch off a specific gene regulator.
"We find when you treat with CBD, you down regulate the expression of this protein, and that inhibits the disease process," explains McAllister.
Desprez believes the effect may have to do with a natural defense mechanism in the plant, which he says protects it from insects by retarding their development.
"So maybe the plant is making these compounds to combat the development of insects and we can use the compound to target cancer cells that act like embryonic cells," Desperz theorizes.
The team believes the current results, coupled with the non-toxic nature of CBD, is now encouraging enough to warrant human trials, which they hope to secure funding for in the upcoming months. In anticipation, the team has designed two trial models, one for brain cancer and the other for breast cancer.
http://abclocal.go.com/kgo/story?section=news/health&id=9057615
There is a video of this news story in the link above, I couldn't find the video on youtube.
Anyway
Herbs-2 Pharmaceuticals-0
But more than five years ago, researchers at California Pacific Medical Center in San Francisco began focusing their attention on a far tamer compound in the marijuana plant, an ingredient called cannabidiol.
"Cannabidiol is a non-toxic agent from cannabis that is not psychoactive," says Sean McAllister, Ph.D., a lead researcher in the group's recent study.
McAllister and colleague Pierre Desprez, Ph.D., now believe they are ready for human trials, using the compound to treat metastatic cancer. The pair has produced a synthetic version of cannabidiol, also known as CBD, which they say targets a specific gene in the body related to the spread of cancer.
"We found this one compound, CBD, had a specific effect on metastatic cancer cells, very aggressive tumor cells. The bad cancer cells, the ones that spread throughout the body," said Desprez.
In their recently published study the team documented that effect on brain cancer in a large scale animal trial. They say brain scans revealed the disruption of the tumor cells after the cannabidiol was used to switch off a specific gene regulator.
"We find when you treat with CBD, you down regulate the expression of this protein, and that inhibits the disease process," explains McAllister.
Desprez believes the effect may have to do with a natural defense mechanism in the plant, which he says protects it from insects by retarding their development.
"So maybe the plant is making these compounds to combat the development of insects and we can use the compound to target cancer cells that act like embryonic cells," Desperz theorizes.
The team believes the current results, coupled with the non-toxic nature of CBD, is now encouraging enough to warrant human trials, which they hope to secure funding for in the upcoming months. In anticipation, the team has designed two trial models, one for brain cancer and the other for breast cancer.
http://abclocal.go.com/kgo/story?section=news/health&id=9057615
There is a video of this news story in the link above, I couldn't find the video on youtube.
Anyway
Herbs-2 Pharmaceuticals-0
Comments
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This is an older video......
There should be some new stuff coming on this...........
http://youtu.be/JxObpkkX8fE -
Ok, after having lost my mother and others to cancer, I am really interested in cancer trials etc.. wondering how is this cannabidiol taken?? Is it injected??
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Ok, after having lost my mother and others to cancer, I am really interested in cancer trials etc.. wondering how is this cannabidiol taken?? Is it injected??
http://www.medicaljane.com/cannabidiol-cbd-medicine-of-the-future/ < here is another article on cannabidiol
I think you either smoke it or ingest it. This stuff reminds me of the documentary on ? oil called "run from the cure", you should check that out as well.
http://www.youtube.com/watch?v=0psJhQHk_GI
^ this is the "run from the cure" documentary.
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Cannabanoids are like all plants they don't produce enough to do anything from smoking it or eating it. If they find anything, it'll have to be in large concentrations.
All sorts of plants have great properties we can and do use everyday cannabis is no different, don't get so excited there's still years of research ahead. -
GreenCapitalist90 wrote: »Ok, after having lost my mother and others to cancer, I am really interested in cancer trials etc.. wondering how is this cannabidiol taken?? Is it injected??
http://www.medicaljane.com/cannabidiol-cbd-medicine-of-the-future/ < here is another article on cannabidiol
I think you either smoke it or ingest it. This stuff reminds me of the documentary on ? oil called "run from the cure", you should check that out as well.
http://www.youtube.com/watch?v=0psJhQHk_GI
^ this is the "run from the cure" documentary.
Cheers on the feedback, will check it out! -
Ive always felt weed was in a special class of righteousness, but i have trouble trusting these studies now that the medical monopoly profits from it's use. They may just be lieing in the other direction now, cuz all their studies showed it was harmfull until they got dibs on it's profits!